Yes, you can lock your luggage...as long as you use a TSA approved lock. These TSA-approved luggage locks let you set your own custom 3-dial combination, so you won't forget it. Plus, there's an indicator dot to show if your luggage has been inspected by the TSA. The dot is set to green, but if the TSA opens your lock, the dot turns red. The indicator resets to green the next time you lock your luggage.